Studies on γ-oryzanol: Effects of γ-oryzanol on stress ulcer
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چکیده
منابع مشابه
Antioxidant Activity of γ-Oryzanol: A Complex Network of Interactions
γ-oryzanol (Orz), a steryl ferulate extracted from rice bran layer, exerts a wide spectrum of biological activities. In addition to its antioxidant activity, Orz is often associated with cholesterol-lowering, anti-inflammatory, anti-cancer and anti-diabetic effects. In recent years, the usefulness of Orz has been studied for the treatment of metabolic diseases, as it acts to ameliorate insulin ...
متن کاملγ-Oryzanol Enhances Adipocyte Differentiation and Glucose Uptake
Recent studies show that brown rice improves glucose intolerance and potentially the risk of diabetes, although the underlying molecular mechanisms remain unclear. One of the phytochemicals found in high concentration in brown rice is γ-oryzanol (Orz), a group of ferulic acid esters of phytosterols and triterpene alcohols. Here, we found that Orz stimulated differentiation of 3T3-L1 preadipocyt...
متن کاملEffects of Ferulic Acid and γ-Oryzanol on High-Fat and High-Fructose Diet-Induced Metabolic Syndrome in Rats
BACKGROUND The high morbidity of metabolic dysfunction diseases has heightened interest in seeking natural and safe compounds to maintain optimal health. γ-Oryzanol (OZ), the ferulic acid (FA) ester with phytosterols, mainly present in rice bran has been shown to improve markers of metabolic syndrome. This study investigates the effects of FA and OZ on alleviating high-fat and high-fructose die...
متن کاملAntioxidant Effects of Gamma-oryzanol on Prostate Cancer Cells
Gamma-oryzanol is the major component, 2%, in the extract from rice bran. Rice bran oil contains a mixture of several phytosteryl ferulates. Several reports mention the rice bran oil health beneficial activities, reduction of plasma cholesterol, inhibition of platelet aggregation, and particular antioxidant functions. In Japanese traditional medicine, rice bran oil has been used to ameliorate t...
متن کاملNinety-day oral toxicity study of rice-derived γ-oryzanol in Sprague-Dawley rats
A 90-day oral toxicity study of γ-oryzanol, a rice-derived triterpenoid ferulate, was performed by oral gavage administration to male and female Sprague-Dawley rats at doses of 0, 1000, and 2000 mg/kg body weight/day. All rats administered γ-oryzanol survived throughout the study period. Both male and female rats showed no toxicologically significant changes of the general signs, examination fi...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1976
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.72.475